The best way to get around in Cayo is by driving your car, but some of it depends on where you live. If you live right in San Ignacio, everything is within walking distance or you can just grab a taxi, which is quite affordable. If you live out of town, you definitely need a car.
We have a pickup truck and a little open jeep. If you have a Porsche or any car that is almost glued to the street, forget it in Cayo because there are lots of potholes here. There are also speed bumps where you have to slow down as you drive over. The best vehicle to have in Cayo is a 4WD SUV.
(Bridge on Hummingibrd Highway, pictured.)